50 years old, male, with epilepsy and chronic alcohol abuse; extensive (both lower limbs) full-thickness flame burn. This is one of the most suggestive and difficult cases, because this man had a very deep burn destroying his left knee joint and without LIGASANO® we would have to amputate his left lower limb; instead of this he left the hospital (after 6 month and 8 operations) with his two legs, “completely repaired”.